Which organ is primarily responsible for detoxifying blood?

The liver is primarily responsible for detoxifying blood due to its crucial role in metabolizing various substances, including drugs, toxins, and waste products. It processes nutrients absorbed from the digestive tract and converts harmful chemicals into less toxic forms or prepares them for excretion. Through a series of biochemical reactions, the liver transforms fat-soluble substances into water-soluble forms, allowing them to be excreted through urine or bile. Additionally, the liver synthesizes proteins that are essential for blood clotting and the immune response, further contributing to its vital functions in maintaining overall health and homeostasis. This complex detoxification process highlights the liver's importance in protecting the body from potential harm caused by various substances circulating in the bloodstream.